How Can Severe Depression Along With Fatigue Be Treated?

Dear Dr. Andrew, How are your Sir. I need some expert advice from you about my mother. My mother is 68 years old. Many years ago she had undergone Golbladder Stone operations; Tumor operations in stomach; Eye operations and Appendix operations. She suffered stroke 5 years back; She have issues of brain not functioning properly; have sound sleep issues for many many years; she is also suffering from Corn for many many years; she was suffering from acute high pressure, now high bottomline; have some neurological and physiological issues; suffering from depression; weakness ( cannot work as she was working earlier ); she cannot stand or sit for more than 15-20 minutes at a go; she had lost urge to eat foods; she cannot gossip for more than 10 minutes, as stated she is unable to use her brain; recently detected high Thyroid and Vitamin D deficiency. Course for Vitamin D done as advised Vitamin D3 60 K capsules once a week for 8 weeks. As recommended by doctors she is having Thyronorm 75( For Thyroid ) at around 7 am and Amlodipine S 2.5 ( For pressure ) at 8 am. After breakfast she used to Serta 50 and Premipex .125. Post Lunch she used to take a multivitamin Cobadex Forte. After dinner she used to take Nexito 10 and Premipex .125 on regular basis. Sleeping tablets Alzolam.25 / 5 or Nightrest 5 as and when required. Need your valuable guidance. Regards, Prabal Basu Ray Kolkata, India