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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Effective And Safe Is EFROX4000 For Dialysis?

Hi my dad is 60yrs old & its been an year he is undergoing dialysis. But everytime its that his haemoglobin is going down. The doctors have told him to go for dialysis twice in a week & for every dialysis the doctor give him "injection name EFROX4000" to increase his heamoglobin. But this injection is not helping at all. I am too worried about my dad's health, please suggest me the best & safe option to increase his haemoglobin.
Mon, 2 May 2016
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General & Family Physician 's  Response
Hi & Welcome.
I appreciate your concern for your beloved father.
Injection EFROX (Erythropoietin) is a hormone which helps in the formation of red blood cells by the bone marrow and thus prevents anemia.
Normally it is produced by the kidneys. Since your dad is suffering from renal failure (chronic kidney disease) his kidneys do not produce this hormone sufficient enough to stimulate the red blood cells production in the bone marrow hence it has to be given in the form of replacement or injection.
It is quite effective in increasing the red blood cells production and thus hemoglobin level and generally found to safe.
It is usually given in dose of 150 units/kg body weight 3 times a week.
It may take 2–6 weeks or longer to get the full benefit of EFROX injection i.e., to INCREASE the HEMOGLOBIN level.
So, do not stop giving him this injection as it will help control his anemia only as long he is given it.
Consult his treating nephrologist to adjust the dose as per his body weight and continue to give him this medication as prescribed.
Hope this advice will work for him.
Wishing him best of health.
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How Effective And Safe Is EFROX4000 For Dialysis?

Hi & Welcome. I appreciate your concern for your beloved father. Injection EFROX (Erythropoietin) is a hormone which helps in the formation of red blood cells by the bone marrow and thus prevents anemia. Normally it is produced by the kidneys. Since your dad is suffering from renal failure (chronic kidney disease) his kidneys do not produce this hormone sufficient enough to stimulate the red blood cells production in the bone marrow hence it has to be given in the form of replacement or injection. It is quite effective in increasing the red blood cells production and thus hemoglobin level and generally found to safe. It is usually given in dose of 150 units/kg body weight 3 times a week. It may take 2–6 weeks or longer to get the full benefit of EFROX injection i.e., to INCREASE the HEMOGLOBIN level. So, do not stop giving him this injection as it will help control his anemia only as long he is given it. Consult his treating nephrologist to adjust the dose as per his body weight and continue to give him this medication as prescribed. Hope this advice will work for him. Wishing him best of health.