Hi, I guess your concern is about getting pregnant, naturally without IVF, at the age of 42 years. You have mentioned that you are taking medicine - M2 tone for regularization of menses. The dose, and since when you have started taking the medicine is not shared by you. After taking the medicines whether the menses have become regular or not, it is also not shared by you. It is nature s rule, as we get older the functions of our body will be decreased quantitatively and qualitatively. The ovaries also decrease in its function as women become old. The reproductive age group, that is maximum chances of conceiving is more usually at 20 to 40 years. Around the age of 50 to 52 years, women stop her menses. This indicates she can t conceive anymore. The age 45-48 years is a transition zone from highly reproductive age group to the age group where menses stop. And here the chances of getting pregnant are not as high as reproductive age group and not low as 50- 52 yrs of age. But still there is a chances of getting pregnant in this transition age, and you are at 42, so there is a hope of getting pregnant. Be positive and don t lose hope. However, irregular menses at this age decreases the chances of pregnancy. But, as you are on medicine for irregular menses, once the menses becomes regular, the chances of getting pregnancy increases. So there is double positive hope for you. Some people though they are in reproductive age group, because of problem, either in husband and wife, chances of getting pregnancy decreases. You have told that MY AND MY HUSBAND REPORTS ARE FINE . So there is triple positive hope. As you have lost your first child and you are at the transition zone, its better to go for a accelerated method of pregnancy. The accelerated methods are-IVF, GIFT, ZIFT, ICSI. The advantage of accelerated methods is getting twins of triplets is also there. My suggestions: 1. Have patience. Wait till the menses becomes regular. Then pray to God for natural method of getting pregnant. 2. At the age of 42, transition zone I would recommend u for accelerated methods - assisted reproductive techniques (ART) - IVF, ZIFT, GIFT, ICSI and to visit nearby infertility specialist to know pros n cons of each. I pray God to give strength to your family about the loss of first child and bless you with a cute and healthy baby as soon as possible. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Sudha Rani Panagar