Hello, Welcome to healthcare magic. I understand from your query that you are interested in skin lightening. Glutathione is a potent anti-oxidant and is showing good results in skin lightening. It can even out your skin tone and make it appear better. You could try the tablets taken twice a day. Since it a relatively new medicine, the long term side effect profile is not very much clear. No major adverse effects have been reported till date. However, please consult a dermatologist and do not buy from internet stores as the contents may be standardised. You could also benefit from treating your acne and acne spots as this will improve your overall skin tone and appearance. You could use a gel containing 1% clindamycin in the morning and 2.5% benzoyl peroxide at bedtime for active acne. For the spots, use a gel containing 2 % kojic acid twice a day. Use a good gel based sunscreen every 3 hours during day time. You could also benefit from chemical peels done by a dermatologist. Hope this helps you. Take care.