My sister is very depressed and has been sucial on three separate times last time did cut one wrist she is taking buspirone hcl 10 mg 3 times a day ,bupropion xl 300 mg 1 a day, atorvastatin 80mg 1a day, levothyroxine 75mg 1a day,trazodone 150mg 2 at night,chantix 1mg tablet 1a day and last hydrOXYzine Pam50mg caps she has not done any better infact she has got worse what about her meds should I be concerned