Hi Doctor, I had thyroidectomy in 2010 to remove Papillary thyroid carcinoma, since then I had tested different dosage of synthroid and levothyroxine. I used 112mg 3 times a week and 125mg 4 times a week for about 2 years and a half. There was no recurrence until April 2013, the ultrasound result shown there is a 0.5 x 0.3 x 0.3 cm poorly defined nodule and a 0.6 x 0.3 x 0.2 cm poorly defined nodule in the right thyroid bed that were not present previously, it shown the same result in April 2014. My lab test in 2013 shown: TSH is 0.07, Free T4 is 1.53, thyroglobulin less than 0.9 My blood test in 2014 shown: TSH is 0.05, Free T4 elevated at 1.93, thyroglobulin is less than 0.9 with negative antibody. I was told these two tiny nodules are not something to be really concerned. However, my doctor changed my dosage to 112mg 4 times a week and 125mg 3 times a week after April 2014 visit. She said I am too young to be on such dosage. My question are: 1. Was I over-medicated in the past? Why my doctor said .. I am too young to be on such dosage... 2. After changed the dosage to 112mg 4 times a week instead of 3 times a week, I have bad headache and feeling tired very easily. I could be just got up from bed and cooked a breakfast, I get headache, or I get it just after done a grocery shopping. 3. Should I go back to the old dosage which 112mg 3 times a week and 125mg 4 times a week to stop my frequent headache? Thank you so much, Victoria Yang