Hi & Welcome to HCM. You seem to be suffering from muscle cramps which appear to be associated with the vigorous physical activities during your working hours. The medication Evion LC is a combination of Vitamin E and L Carnithine. It is a nutritional supplement, which is found to be effective in the treatment of muscle cramps associated with lack of these vital nutrients. Acuvin contains Paracetamol & Tramadol which are analgesics (relieve the moderate to severe pain). Please do continue this medicine and in addition to this do apply Diclofenac gel over your calf muscle at night. The muscle cramps can be prevented by the following measures: Wear shoes with proper support. Do exercise which involves flexing the ankle by pulling the toes up toward the head while still lying in bed with the leg as straight as possible. Gently massage the affected muscles will often help it to relax, as will applying warmth from a heating pad or hot soak. If the cramp is associated with fluid loss, as is often the case with vigorous physical activity, fluid and electrolyte (especially sodium and potassium) replacement is essential. Take Vitamin D & Calcium supplements or drink milk. Hope the suggestions given above would be useful.