Hi, I have gone through your query. From the limited information you have provided, I can gather that you have irregular periods and are trying to conceive. The medroxy progesterone acetate is just a progestogen to induce withdrawal bleeding i.e period. Clomiphene citrate is an ovulation drug most commonly used in patients with anovulatory infertility, which means patients who are not ovulating regularly as evidenced by your irregular periods. It is a safe drug. However, it can sometimes cause multiple pregnancy and ovarian hyperstimulation. It is helpful in a majority of cases where there is no other cause of infertility like male factor or tubal and uterine anomalies. A full picture can be given if you provide reports of hormonal studies, ultrasound and your husband semen analysis. I suggest you do these tests if not already done. To answer your question, YES. Clomiphene is very effective in treatment of infertility. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing you good health.