Hi, For pregnancy, you need to have addressed male factor, ovarian factor, tubal factor and uterine factor. I am assuming that all these have been checked and are OK. Siphene (Clomiphene) is given when we are anticipating ovarian problems, if you have not been diagnosed with PCOS or ovulation problem, taking Clomiphene will not increase your chances of pregnancy. Duphaston can be given to help implantation, but as such has no role. Please consult a infertility specialist and do not take siphene empirically without a clear diagnosis. As every medicine has side effects which have to be discuuused. Hope this helps. Regards.