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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Qsymia Recommended With A Family History Of Heart Diseases?

I am a 36 yo female. I have a strong family hx of heart disease and dm2. I have attempted to stay active and avoid a high caloric intake, but my metabolism continues to slow as I get older. I fluctuate between bmi of 28 and 30. I am 5 10 and my abd girth is about 37 which puts me at an even greater risk for CV issues. I am also experiencing fatigue with moderate activity, arthritis, and elevated b/p and resting HR. I would like to start Qsymia to assist in my achieving my weight loss goals. This includes loosing about 40lbs this year or to have a bmi closer to 26. I would continue to exercise about 2-4x/week. Would you recommend this drug for me?
Thu, 12 Nov 2015
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General & Family Physician,  's  Response
Hi

Qsymia is a medicine that contains topiamate and phentermine. Phentermine is a drug that stimulates the central nervous system.

It does have the property of increasing the heart rate. At this point from the literature available, the way this molecule behaves in patients with heart disease is not known and so there is a need to carefully monitor the heart rate in such situations and exercise greater caution.

In your case, I only see a family history of heart disease along with overweight features. So I would go ahead and prescribe qsymia if I were treating you. However I would like to momitor your heart rate at regular intervals and take a decision to discontinue or reduce the dose only if I see a substantial increase in heart rate.

Hope I answered your question.
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Is Qsymia Recommended With A Family History Of Heart Diseases?

Hi Qsymia is a medicine that contains topiamate and phentermine. Phentermine is a drug that stimulates the central nervous system. It does have the property of increasing the heart rate. At this point from the literature available, the way this molecule behaves in patients with heart disease is not known and so there is a need to carefully monitor the heart rate in such situations and exercise greater caution. In your case, I only see a family history of heart disease along with overweight features. So I would go ahead and prescribe qsymia if I were treating you. However I would like to momitor your heart rate at regular intervals and take a decision to discontinue or reduce the dose only if I see a substantial increase in heart rate. Hope I answered your question.