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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is An Elevated GGT Level Of 156 Indicative Of Liver Cirrhosis?

Is an elevated GGT of 156 indicative of cirrhosis when all other liver enzymes are within normal ranges and MRI and abd. ultrasound are negative except for residual mildly fatty liver? Patient was diagnosed with alcoholic hepatitis a year ago and has been totally abstinant since. She presented with elevated ammonia levels, possible mild H.E. but no ascites, variceles, jaundice or flapping. On Xixan 550mg twice a day for a year and Dr. will maintain her on it indefinitely. How do we know if she progressed to cirrhosis?
Fri, 28 Aug 2015
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Radiologist,  's  Response
Hello

Increased GGT doesn't indicate liver cirrhosis.
Increased GGT may indicate liver injury.It is specific for alcoholic liver disease.
Patient may need latest ultrasound,fibroscan to assess exact stage of disease.
Fibroscan assess elasticity of liver tissue and it is very helpful in assessing disease progression.
Liver biopsy can be done after evaluation.

I suggest tablet ursodeoxycholic acid 300 mg twice daily for three months to my patients.It helps in regeneration of liver cells.
She may need more medicines after evaluation.
It is good that patient had quit alcohol.This is very important for her health.

Get well soon.
Take Care
Dr.Indu Bhushan
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Is An Elevated GGT Level Of 156 Indicative Of Liver Cirrhosis?

Hello Increased GGT doesn t indicate liver cirrhosis. Increased GGT may indicate liver injury.It is specific for alcoholic liver disease. Patient may need latest ultrasound,fibroscan to assess exact stage of disease. Fibroscan assess elasticity of liver tissue and it is very helpful in assessing disease progression. Liver biopsy can be done after evaluation. I suggest tablet ursodeoxycholic acid 300 mg twice daily for three months to my patients.It helps in regeneration of liver cells. She may need more medicines after evaluation. It is good that patient had quit alcohol.This is very important for her health. Get well soon. Take Care Dr.Indu Bhushan