Hi, yes. I started cellcept 500 mg bid x 5d on March 10th, increased to 1000mg bid 5 days later. I am having a hard time with taking it 1 our before food or 2 hours after as I have IDDM, hypothyroidism, and newly dx Myasthenia Gravis (lucky me). My question is is cellcept less effective if taken with food or is it because of GI side effects if taken with food? I sometimes feel a spasm in ABD region 15-20 min after taking pills and can palpate a tightening knot spasm for 15-30 seconds, no severe pain. I went from 125# to 115# with lack of apetite. Obviously I need food and insulin and am trying to incorporate cellcept, just looking for advice.