Dear User, Thanks for using health care magic. The continuous use of Eptoin do not cause any problem other than few side effects like gum hypertrophy, hyperglycemia and weight change. This medication is safe even on long term use but you need to check with your doctor. If your astrocytoma was resected properly than I think it should be removed in graded manner as most of the seizures occur during first year after surgical intervention of astrocytoma. Hope I have answered your query. If you have any further questions I will be happy to help . Thanks