Thank you for your query. Creatine is found mainly in Muscles. Creatinine is a metabolic product of Creatine. Creatinine is removed from the body mainly by the Kidneys. For this reason, it has been used as an indirect marker for assessing renal function. Normally, an increase in creatinine above the normal range would indicate a reduction in the glomerular filtration rate (GFR) of the kidneys functional units. The GFR determines, how effective the kidney is removing metabolites and maintaining homeostasis. For, sedentary to moderately active individuals, the usual lab values provide a good reference. However in athletes with more muscle mass compared to the non atheletic people, there is more creatinine in the blood to start with and may not necessarily indicate a decline in renal function. Diet rich in animal protein , protein or creatin supplements, certain medications can all increase the level of creatinine in the body ( either directly or by reducing its excretion at the kidney level). Serial serum creatinine levels and monitoring of other renal parameters will help to determine if you have a reason to worry. Try to eat a well balanced meal and get all your nutrition from natural products rather than concentrated forms. hydrate yourself adequately. If you are on any medications, consult your doctor to see if it contributes to the elevated levels. Go for routine checks and monitor closely. If you have diabetes, hypertension or high cholesterol levels, risk of kidney damage is present. Early detection will help prevent progression. Hope this helps. Wish you good health and get back to us if you need further clarification