Hello dear I understand your concern Earlier used unwanted 72 will not work for the sex done on the next day. You can take unwanted 72 to prevent the pregnancy, but chance of the side effects and hormonal imbalance are high as you used earlier also. But side effects are tolerable. So take unwanted 72 as you had unprotected sex. After taking pill take following advises: Proper rest Drink plenty of water Take healthy diet If abdominal cramp occur then meftal spas will helpful Maintain proper pelvic hygiene by using V vaginal wash to prevent the vaginal infection Use safe sex practice in future to prevent the unwanted pregnancy. Use Unwanted 72 only for emergency purpose and avoid frequently use. Hope this may help you Contact HCM for further health query Best regards Dr. Sagar