I am a 46 year old female in peri menopause. Cycle is still around every 21 days unless I use Estradoil cream to balance my hormones once in awhile. It is a biodentical that I can use on my wrist if estradoil or abdominal if progesterine. If I use the estradoil cream it seems to throw off my cycle but it helps with palpitations that I have when low. What other options do I have to help with side effects? I tried Estroven for dryness and it worked great except I sufferered with horrible menstral bleeding for months after only using it lightly for about a week. Otherwise I m in good health.