Hi Doctor Saurabh Gupta, I am aware of the side effects and I am using Ace Proxyvon off and on without any constipation , headache , rhinitis and flu like symptoms What I want to know. Is it harmful in the long run. I am told by various friends not Doctors that its effects the liver . Dr. Gupta, this is only drug which gives me relief for 24 hours No other pain killer is giving me any relief. My question is how often can I take this and which is the best way to regulate the consumption of this medicine. Regards Surinder S Puri India, Mumbai Mobile No. 91-0000 Email: YYYY@YYYY