Hello, You have migraine headache and have been prescribed migraine relieving pills (medicines) by your treating doctor. You are uncomfortable and want to know if it is safe for you. You have also gained weight around the belly and waist. Any medicine when taken for a very long period is liable to cause side effects. Do not get addicted to medicines. You can take migraine medicines for relieve when having very severe headache. Controlling the trigger factors that cause migraine can be helpful to prevent it. You should go for strict diet change, avoid taking processed food, alcohol, caffeine, red wine, etc. Managing stress, doing regular stretch exercises, walking regularly, taking massage therapy, staying away from direct exposure to sunlight, strong smell of oil, paint, etc., taking adequate amount of fluids and water, taking quality sleep help in reducing migraine attack considerably. To reduce belly fat and fat around the waist book physical therapy session, do regular exercise and walking. Control the portions you eat, avoid trans fat, refined flour, carbohydrate, do not take alcohol or full fat dairy products. Exercises and diet control will help to reduce weight gain. Stay away from addictions if any. When taking migraine preventive medicines, weight should be monitored carefully as patients may show a gain in weight. Topamax is also prescribed for migraine, its side effect is weight loss so it should only be taken when a doctor prescribes it. as it can cause blurred vision and affect the thinking and reactions. Ketogenic or ketosis diet is not recommended while taking Topamax. Take medicines only after consultation with a doctor. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Nupur K., General & Family Physician