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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Penicillin Injection Required For A VDRL Detected By Blood Tests?

My father who is 88 was told by the doctor that he has VDRL and needs penicillin injection. There are no other symptoms. It was just found out from regular blood tests results. My father refused to take the treatment because he thought it is unnecessary. Please kindly advice.
Thu, 3 Jul 2014
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Psychiatrist,  's  Response
HI THANKS FOR YOUR QUERY. SIR I WOULD LIKE TO TELL YOU THAT ALL TRUE POSITIVE CASES OF VDRL,REQUIRES TREATMENT WITH INJECTIONS OF PENCILLIN PROCAINE. FIRST OF ALL , CASES OF +VDRL HAVE TO FOLLOWED WITH TPI(TREPONEMA PALLIDUM IMMOBILISATION) TESTING FOR CONFIRMATION OF SYPHILIS CAUSING BACTERIA IN THE BLOOD.IN CASES OF "NEUROSYPHILIS..ESPECIALLY IN THE ELDERLY ie; POSITIVE CEREBROSPINAL VDRL,OR IN PRESENCE OF CEREBROVASCULAR/BRAIN RELATED SYMPTOMS,IT IS EXTREMELY WORTH SUGGESTED TO TAKE INJ.PROCAINE PENICILLIN WITH TAB PROBENECID FOR 3 WEEKS. THE RESPONSE TO THERAPY SHOULD BE MONITORED BY RETESTING OF VDRL TITRES....RAPID PLASMA REAGIN (RPR) TITRES SHOULD CAN ALSO BE USED TO MONITOR THE RESPONSE TO THERAPY. IT TAKES AROUND 6 MONTHS FOR THE TITRES TO TEST NEGATIVE---SEROCONVERSION.
PLEASE LOOK FOR THE DEVELOPMENT OF ANY ALLERGIC REACTIONS DURING THE THERAPY.
AVOID PENICIILLIN IN ALL CASES OF DOCUMENTED PENICILLIN HYPERSENSIVITY-HARISCH JACQHEIMER RESPONSE.
ALSO KEEP A WATCH ON DEVELOPMENT OF SKIN LEISONS OR OTHER ORGAN DAMAGE SIGNS OF LIVER INVOVELMENT LIKE JAUNDICE TO DETECT THE ONSET THE SECONDARY SYPHILIS AT THE EARLIEST.
CONSULT AN EXPERT VENEROLOGIST IN SUCH A CASE.
THANK YOU.
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Is Penicillin Injection Required For A VDRL Detected By Blood Tests?

HI THANKS FOR YOUR QUERY. SIR I WOULD LIKE TO TELL YOU THAT ALL TRUE POSITIVE CASES OF VDRL,REQUIRES TREATMENT WITH INJECTIONS OF PENCILLIN PROCAINE. FIRST OF ALL , CASES OF +VDRL HAVE TO FOLLOWED WITH TPI(TREPONEMA PALLIDUM IMMOBILISATION) TESTING FOR CONFIRMATION OF SYPHILIS CAUSING BACTERIA IN THE BLOOD.IN CASES OF NEUROSYPHILIS..ESPECIALLY IN THE ELDERLY ie; POSITIVE CEREBROSPINAL VDRL,OR IN PRESENCE OF CEREBROVASCULAR/BRAIN RELATED SYMPTOMS,IT IS EXTREMELY WORTH SUGGESTED TO TAKE INJ.PROCAINE PENICILLIN WITH TAB PROBENECID FOR 3 WEEKS. THE RESPONSE TO THERAPY SHOULD BE MONITORED BY RETESTING OF VDRL TITRES....RAPID PLASMA REAGIN (RPR) TITRES SHOULD CAN ALSO BE USED TO MONITOR THE RESPONSE TO THERAPY. IT TAKES AROUND 6 MONTHS FOR THE TITRES TO TEST NEGATIVE---SEROCONVERSION. PLEASE LOOK FOR THE DEVELOPMENT OF ANY ALLERGIC REACTIONS DURING THE THERAPY. AVOID PENICIILLIN IN ALL CASES OF DOCUMENTED PENICILLIN HYPERSENSIVITY-HARISCH JACQHEIMER RESPONSE. ALSO KEEP A WATCH ON DEVELOPMENT OF SKIN LEISONS OR OTHER ORGAN DAMAGE SIGNS OF LIVER INVOVELMENT LIKE JAUNDICE TO DETECT THE ONSET THE SECONDARY SYPHILIS AT THE EARLIEST. CONSULT AN EXPERT VENEROLOGIST IN SUCH A CASE. THANK YOU.