I started using estradot 50 today. Hormone replacement for menopause and osteoporosis. I also using other medications for high blood pressure, topisalic lotion for my psoriasis, omega 3, calcium and vet d. My concern is it safe to interact with all the medications iam taking. Also I was taking apo-gabapentin100mg and pms-sulfasalazine ec 500mg for my bursitis, a month ago. I stop taking this medication because it lowers my white blood corpuscles .it never help my bursitis any way. My sister was diagnosed with breast cancer 2 years ago, and undergoing treatment .l am also have varicose veins but it does not bother me at all, it is just very visible on my legs. How. Am I safe with the hormone therapy that I am taking right now.