Hi, Brief answer: Amlodipine is very rarely associated is erectile dysfunction. Detailed answer: Blood pressure lowering medications can cause low libido and erectile dysfunction. Diuretics (or water pills) and beta blockers are two classes of blood pressure lowering medication that are known to cause problems with sexual performance. Amlodipine is a calcium channel blocker and this group of medications rarely causes erection problems. Rather than a medication side effect of amlodipine, erectile dysfunction might actually be a sign of inadequate control of blood pressure. High blood pressure damages blood vessels, reducing the blood flow to the penis and thus making it more difficult to achieve and sustain an erection. I suggest that you talk with your doctor about your symptoms and to check your blood pressure. Hope this helps answer your query. Let me know if I can assist you further. Take care, Dr. Aaron Shapiro