Hi Linda, Aranesp is a man made protein used to increase the amount of RBC production in patients with low hemoglobin. It is a form of erythropoietin. During increased production, nutritional deficiency if present could lead to nutritional anemia. I would advise you to ask him to start B-complex group of vitamins along with iron and folic acid tablets. Looks for any allergic reactions, when you start these. Nutritionally also you can look into modifying the diet like green leafy vegetables, egg, fish so the Aranesp injection can perform its function more effectively. Increased risk of thrombosis is seen on treatment due to Aranesp. Soo look for any symptoms of chest pain, syncope or breathlessness. If any of the symptoms are present, immediately meet your doctor. Any further queries, happy to help again.