Hi...oedema in the lower extremities following medical drugs can occur secondary to renal toxicity of the drugs... But since the renal functions are normal this may not to be as it is thought of.. Hence other causes for the swelling's have to be considered... It can occur due to secoday to liver effects or due to effects on th heart.. The heart dysfunction is not due to antibiotics but the lung dysfunctions. These to be evaluated to know the cause... Discuss with yout doctors..