I recently began vaginal Premarin for Urethrotrigonitis. I am also taking Premarin orally for harmone therapy since my hysterectomy 4 years ago. Shortly after starting the vaginal dosage, I began to experience mild welts on my body that I thought were bug bites. Over the last several days, I have very large welts over my stomach, breast, legs and buttocks. Is it possible that the premarin cream is causing this? If so, What are my other options for treating Urethrotrigonitis?