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Dr. Andrew Rynne

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Outbreak Of Itchy Rash On Arms, Legs, Stomach,chest Increased During Periods. On Zyrtec. Possible G6PD Enzyme Deficiency?

I have had an itchy rash on my skin for years; mostly my arms, legs, stomach, chest, its worse when I'm on my cycle that's when the bumps appear. I was just reading about G6PD enzyme deficiency is it possible I have this? I have been to a dermatologist and I take Zyrtec every day for the itching but it has not helped with stopping the outbreaks.
Fri, 26 Jul 2013
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Dermatologist,  's  Response
Hi,

Welcome and thanks for posting your query to Healthcare Magic.

After reading your query it appears the possibility of "Urticaria". It is a common condition caused by bursting of allergy producing cells known as "mast cells". As the chemical inside them is released it produces a rash which you have mentioned. There can be multiple factors producing this condition which are included in day to day life and some times it is really difficult to find one exact cause. In your case stress just before menses can cause the bursting of the cells.

For the betterment kindly follow the suggestions below:
-Apply over the counter calamine lotion 3-4 times a day.
-You can do cold water compresses to reduce the intensity of itching.
-Do not scratch or rub the skin as it can lead to further aggravation.
-The best measure is to take oral anti histamine like loratadine or levocetrizine under medial advise.

G6PD enzyme deficiency generally do not cause any rash per say so do not worry about the same.
In between next time if the rash appears before menses then you can consult a dermatologist who can diagnose it exactly.
Hope these information will help.

"With good health wishes"

Dr Sanjay Kumar Kanodia
MD (Dermatology & STDs)
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Outbreak Of Itchy Rash On Arms, Legs, Stomach,chest Increased During Periods. On Zyrtec. Possible G6PD Enzyme Deficiency?

Hi, Welcome and thanks for posting your query to Healthcare Magic. After reading your query it appears the possibility of Urticaria . It is a common condition caused by bursting of allergy producing cells known as mast cells . As the chemical inside them is released it produces a rash which you have mentioned. There can be multiple factors producing this condition which are included in day to day life and some times it is really difficult to find one exact cause. In your case stress just before menses can cause the bursting of the cells. For the betterment kindly follow the suggestions below: -Apply over the counter calamine lotion 3-4 times a day. -You can do cold water compresses to reduce the intensity of itching. -Do not scratch or rub the skin as it can lead to further aggravation. -The best measure is to take oral anti histamine like loratadine or levocetrizine under medial advise. G6PD enzyme deficiency generally do not cause any rash per say so do not worry about the same. In between next time if the rash appears before menses then you can consult a dermatologist who can diagnose it exactly. Hope these information will help. With good health wishes Dr Sanjay Kumar Kanodia MD (Dermatology & STDs)