I get a sensation of pain directly in my left palm whenever I feel emotionally hurt, neglected, betrayed, misunderstood or not cared for by my boyfriend, whom i love dearly and who loves me dearly. I am being treated for major depressive disorder for the past 3.5 years and am also under treatment for lupus, but just borderline, for the past 1 year. The pain starts instantly as the emotion arises. it is focused around the thumb of the left hand and in the palm and not much in the fingers. at times, the right palm aches too. this has been happening for the last three years. my lupus doctor put me on pregabalin 75mg for this pain for 10months but it didnt help so we slowly tapered it and stopped. what could this be. strangely, it happens only in incidents involving my boyfriend.