Hi, It is possible that the pain and burping you are experiencing could be related to indigestion or gastroesophageal reflux disease (GERD), which can be exacerbated by taking Prilosec. However, given that you have recently received a mechanical aortic heart valve and are a diabetic, it is important to be cautious and rule out any cardiac issues. Sharp chest pain can be a symptom of angina or other heart conditions. The fact that the pain goes away after burping could suggest that it is not heart-related, but it is still important to have a thorough evaluation by a healthcare professional. I recommend that you speak with your doctor about your symptoms, particularly if they are becoming more frequent. They may recommend additional tests, such as an electrocardiogram or stress test, to evaluate your heart health. They can also evaluate your Prilosec use and make adjustments if necessary to help manage your symptoms. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Diwashish Biswas, Internal Medicine Specialist