Hi. I am suffering badly with side affects of having a 28 day zoladex stomach injection 3 weeks ago. I have been given anastrozole 1mg to take daily also. I have advanced er+ breast cancer. The bone pain and stiffness is constant and nagging, very dibilitating. Also have developed itchy skin rash and a tooth abscess. Paracetamol alone doesn t touch pain. I understand why this course of treatment has been prescribed with my er+ cancer! but the side effects, the constant pain, are so seriously affecting my quality of life, I am considering not continuing with this treatment, although am not sure of any alternative?