Thank you for your question! Regarding treatment dosages, more objective recommendations would be drawn based on clinical history of the disorders for whom it is prescribed, clinical results of the prior doses used, functional
kidney and
liver lab tests, body weight, comorbidities, any adverse effects, drug interactions and so on.
Regarding Rytmonorm, if you are using it for example prevention of AF recurrences or
SVT, and you have an average weight lets say 75 kg, you don't have serious renal or hepatic comorbidities, no other rate controlling drugs, the recommended dose is 150 mg x 3 per day (1 tb/morning, 1 tb/midday, 1 tb/evening). The recommended quantitative measure of effect achieved by changing doses of anti arrhythmics is performed by ambulatory ECG monitoring.
Regarding Aprovel
dosing, the guide will be dose/effect ratio; so if BP values are persistently high the you can increase to 450 or 600/day. In every decision about dose change you should consult your doctor as he know all the conditions I mentioned about. Hope to have been helpful to you. Greetings from Dr. Iliri