Hi. Thanks for being there for me. I just went to a cardiologist today. He took me off aspirin. OK He changed my Metoprolol Tart 25 mg. to Toprol XL 25 mg x 2 once a day. I was taking the Metoprolol in the evening , about 8PM, but the instructions called said to take with food. I moved the new pill to the morning so I could take it with breakfast. I also take Loratadine 10 mg., Calicium 600 +D3, Sr. Multivitimin, Omeprazole 20 mg. and Pradaxa 150mg (1 AM and 1 PM) Will my changing the time frame interfere with any other meds? Charlotte NOTE: THOUGHT THIS WAS FREE. SORRY TO HAVE BOTHERED YOU. WILL CALL DR. IN MORNING