I have been battling depression, anxiety, stress, and irritability for years. I recently got pregnant, got married, graduated from nursing school, and got a job. Oh yes, and we built a house. WOAH! Im exhausted just writing about it. I have been unsuccessfully treated with several antidepressants and the more research I do I find a common correlation between thyroid issues and the symptoms I have described above. My mother has hypothyroidism and take synthroid every day. I am beginning to wonder if my medication is not doing its job is because we have not considered a thyroid problem... However, I have also read that you have to be specific when asking for thyroid levels to be drawn.