My husband has been diagnosed with Parkinson s. He is on Sinemet and Azilect and rigidity, balance, cramped handwriting, shuffling walk are all improved, But his most distressing symptom is a feeling of tightness in the face, right hand and foot that is with him 24/7 except when the affected area is in use (such as when he is eating or talking). This is driving him crazy--it is not painful, but so maddingly annoying and difficult to ignore. Also since he started Sinemet he is constantly queasy, as though he is about to be sea-sick. The doctor increased the dosage of Sinemet thinking the tightness would react to a larger dosage but there was no change.