Hi! Good evening. I am Dr Shareef answering your query. As your husband already had all kinds of investigations done and had a cholecystectomy, with the persisting pain post surgery, I would advise you for the following if I were your doctor: 1) Avoid eating food from outside as recurrent intestinal infections might creep into the intestines giving rise to pain abdomen. To rule this out, I would go for a routine stool test for ova and cyst and treat it if positive. 2) Some of the components of the food he consumes might be causing sensitivity reaction to the intestinal mucosa giving rise to such symptoms. In this case a hit and trial exclusion of diet to see if excluding some component of food from his diet would relieve his symptoms. For this , consultation with a dietician would be worth while to rule out an unsuspected gluten sensitivity or a lactose intolerance. 3)Some modification in your diet like more of roughage, enough liquids, avoidance of oily, fried, and fast food, and avoidance of alcoholic beverages and smoking if you do. 4) A serum amylase and lipase if not done till now. 5) Till then I would advise you for a proton pump inhibitor, an anti spasmodic and a probiotic drug for a symptomatic relief. I hope this information would help you in discussing with your family physician/treating doctor in further management of your problem. Please do not hesitate to ask in case of any further doubts. Thanks for choosing health care magic to clear doubts on your health problems. I wish you an early recovery. Dr Shareef.