Hi There, I have been on Movicol for about 8 years. After trying just about everything to treat it. From countless doctors that put me on probiotics, diet, exercise, antibiotics, anti fungals, anti inflammatory creams, colonoscopies with no real solution. In the last year or two, I think my body is resisting the Movicol and moved to a combination of Movicol and Fibergel. It worked for a small while then I started getting numb like intermittent pains in my left buttocks along with a swollen like pain in my left perineum. Now if I go off the meds I am sure those things will go away but then I sit with severe constipation. I really hope you can help me with this. I ve kind of run out of options.