hello, first if she is having high bp then she needs to be medicine and should have a healthy lifestyle like avoiding fatty, oily and high calorie diet. Have low salt diet and monitor blood pressure regularly thrice a day for one week then once or twice a week. Regular exercises like brisk walking, jogging according your capacity atleast 30 min a day and 5 days a week. Lots of green leafy vegetables, fruits, fish once or twice a week, avoid meat. There shouldn t abdominal fat deposition or obesity. Get your lipid profile and sugars tested once. I think the dose of minipress can be increased and arkamine can be stopped. Also, s-numlo can be 5 mg once a day rather than twice, if not needed can be stopped. Since her pulse rate is going high she ll need seloken which also has bp lowering effect, and also tachyra but dose tachyra should be decreased after 1 week of initiation.