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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Therapy For Nephrotic Syndrome

my son is 3 years old,has Nephrotic Syndrome minimal change ,•ANA is negative , Heavy proteinuria (dipstick +3) albumin is 1.1 we started from 14 days with steroid 60 mg/m2 per day as a single dose the albumin is in increased to 2.17 ,but proteinuria is decreased to +2 in day 10 but return to +3 in day 14, any recommendation please and is 14 days enough to control proteinuria? also is the type of food affect this ,eg my son like to eat egg ( 2-3 eggs a day ) please advice yousef
Fri, 24 Oct 2014
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Pediatrician 's  Response
Hi, I'am Dr Suresh MD , I had gone through your question and understand your concerns.

About 80-90% of children respond to steroid therapy within 3 week. The vast majority of children who respond to prednisone therapy do so within the first 5 week of treatment. If child is does not responds to steroids treatment with in 8 weeks, there is need for further work up including renal biopsy . Some authorities considers further work up in case of non responders in 4 weeks.

A balanced diet rich in proteins( 2-2.5 gm/kg/day is recommended . Reduction of salt intake is advised . once in remission protein can be reduced to 1.5-2 gm/kg /day, and salt restriction can be stopped . He can continue with eggs. For a menu based diet you can consult a dietician.

Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions

Take care.
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Suggest Therapy For Nephrotic Syndrome

Hi, I am Dr Suresh MD , I had gone through your question and understand your concerns. About 80-90% of children respond to steroid therapy within 3 week. The vast majority of children who respond to prednisone therapy do so within the first 5 week of treatment. If child is does not responds to steroids treatment with in 8 weeks, there is need for further work up including renal biopsy . Some authorities considers further work up in case of non responders in 4 weeks. A balanced diet rich in proteins( 2-2.5 gm/kg/day is recommended . Reduction of salt intake is advised . once in remission protein can be reduced to 1.5-2 gm/kg /day, and salt restriction can be stopped . He can continue with eggs. For a menu based diet you can consult a dietician. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions Take care.