My sister is 79, has been on Macrodantin profalaxis for bladder infection for 5 months, one a day after 2 weeks of cipro. She noticed shortness of breath upon doing steps. Read macrodantin can cause this, Doc told her to stop it, follow up with pcp. Her BP was great, pulse, good, oxygen level, 95 No swelling in feet, but a very slight change in ekg. He wants all these tests done.