Sir, my wife, 67, taking seloken 25xl and cilacar 5. Last one month, half of tablets taken from each one. Remaining time, took cilacar 5- 1/2 taken with 4 intervals based on sys pressure while reaching 160. But my doctor advice is to take medicine in the morning 1tab seloken 25xl and evening one tab cilacar 5 tab. It is all carried out in 40 days. On 3.10.14 she took half tab each seloken 25 xl and cilacar 5 in the morning. After 4hours, we noticed the BP is 202 sys, 79dia and pulse 66. My self, husband, went to Dr and informed the situation. Dr advised to take as per priscription - seloken 25 -1 tab& cilacar-5 one tab and evening one cilacar. Today, 5.10.2014, she took as per Dr s advice. intially decresed for 2hrs from 179 to137 sys, 80 to 65 dia and pulse 71 to 68. But, after that pressure increased to 190-71-77 within 1.30hrs. Immediately we went hospital.Today, OP treament is not available. Before that, to avoid any further increase, I took cilacar 5 one tab while going to hospital. After 3/4hr we measured Bp. It is 166-64-79 and further after one hour Bp is reduced to 134-60-70. she is diabetic patient more than 15yrs and 10yrs for Bp. Kindly give your good advice to relieve from this suffering. Now diabetic under control.