Hi welcome to HCm have gone thru your query regarding generalised tickling sensation . I can understand your concern . This is a condition not rare among the masses . Every 3rd person suffers from such sensation , one time or the other due to many causes . It can be tackled if the cause is removed . Dear ,Your MRI clear, Neurological exam checked out fine. All bloods also clear so lets check out of any other cause of concern Like any other health problems , this can be outcome of numerous disorders- physical or psychological , side effect of drug abuse , diabetic neuropathy , diseases of the spinal cord and peripheral nerves , menopause, allergies , skin cancer and extreme alcohol withdrawal with delirium tremens . As the sweat evaporates, it removes the protective oils on the skin can be cause of concern . A close study to find the cause and removal of it and remedies as under will help remove your agony . Eat healthy food which contains all the essential nutrients needed by the body. Especially the food that you eat should be packed with vitamins and minerals. Vitamin B12 is present in meat and other non vegetarian food, while other B vitamins are available in fruits and vegetables. Antioxidants like Aloe Vera juice ,Termeric powder a spoon with milk , Lemon juice all help eliminate toxins , srengthening your immune system and finally providing resistance from diseases .Keep well hyderated . Body massage helps in improving circulation. It also stimulates the nerves and relieves the abnormal feeling. Avoid alcohol and cigarette smoking , stress ,worry , anger , sleeplessness Keep your skin clean by washing with hot or cold water whichever suits , with antibacterial /neem soap and apply neem oil . Take a cup of warm water ,mix 5-6 drops of neem oil and apply on your body as lotion for better result Living with the sensation of crawling skin can be extremely uncomfortable Therefore,if at all , this condition persist , consider medical attention / an expert dermatologist opinion is a must to rule out any obvious medical reason. in order to avoid further discomfort. Hope this helps solves your query .Take care , All the best . Don t hesitate to get back if have any further query