Suggest Treatment For Ovarian Neoplasm

Hi, I have a sister, 48 years old, Gabriela, that was diagnosed with Ovarian neoplasm – (17.12.2013) and she was undertaken a surgery -ovarian adenocarcinoma cyst(total hysterectomy, bilateral anexectomy, rectosigmoidian resection, right diagraphragmatic and prerenal pelvic peritonectomy, parcelar resection of a right diaphragm and omenectomy) T3cN1M1 PLE M1 LYM M1PER M1OTH(diaphragm) – stage IV(01.2014), PCT. Also Gabriela received 12 sessions of chemotherapy with Carboplatin + Taxol(2014), performed re-evaluation(PET/CT scan which showed disease progression) and started chemotherapy with Caelyx. On 20.01.2015 she has the 2nd session of treatment with Caelyx but her marker Ca125 riches a high value of 1400. So the second line of treatment failed . Wondering if you could help me with some info about the 3rd line of treatment for her case and what are the chances/prognostic for her please? I would very much appreciate an answer from you. Warmest regards from Sydney, Elle