Hello, I am really concerned about my grandma. She has a problem with her bladder, since more than a year, we ve tried almost everything, the doctors say they cannot see what the problem is, but she doesnt seem to get better. During the day it is ok, but at night she goes to the toilet too many times, and then she experiences pain and burning down low under the bladder. They checked her urine - nothing was shown, but her struggling continues. Please, if you can tell me what this can be, I would be very thankful!