Hello, Thanks for your query. The burning sensation in leg suggests neuropathy. The reason may be due to defeciency of nutrients or due to vascular compromise or due to any pressure effect. With the history of anxiety and panic the most probable cause is defeciency of nutrients. 1. So you can take multi vitamin supplements consisting of pyridoxine, methyl cobalamine with pregabalin. This supplements will help you in the prevention of symptoms. 2. Along with these you need to have nutritious diet consisting of fruits and green leafy vegetables and more fluids 3. Daily out door exercises (150 min per week). I do hope that you have found something helpful and I will be glad to answer any further query. Take care