Hi, It sounds like you have developed an allergic reaction to Combiflam syrup, which has resulted in a rash on your upper arms with blisters filled with fluid. The heat generated in your body may also be a symptom of an allergic reaction. There are a few steps that can be taken to manage your symptoms: * Stop taking Combiflam immediately: Since you have developed an allergic reaction to Combiflam, you should stop taking it right away. Do not take any more of this medicine without consulting a doctor. * Take antihistamines: You can take over-the-counter antihistamines like cetirizine or loratadine to reduce the itching and swelling associated with the rash. These medicines can help relieve the symptoms of the allergic reaction. * Apply calamine lotion: You can apply calamine lotion on the affected area to soothe the rash and reduce the itching. This will help dry out the blisters and prevent them from getting infected. * Avoid scratching the affected area: Scratching the rash can make it worse and lead to infection. Try to avoid scratching or rubbing the affected area, as this can cause the blisters to rupture and spread the rash. * Consult a doctor: If your symptoms do not improve or if they worsen, you should consult a doctor immediately. Your doctor may prescribe stronger medication or recommend other treatments to manage your symptoms. In the future, it is important to avoid taking any medicines that you know you are allergic to. Always check with your doctor or pharmacist before taking any new medications, especially if you have a history of allergies. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Priyanka, General & Family Physician