Hello, Welcome to Health Care Magic. Thanks for posting your question at this forum. We understand your concern. I am Dr Alok Sinha, MD Psychiatry from India. I wiill guide you about your daughter s health. Whatever information you have given here about your daughter, point towards a serious long lasting mental illness of psychosis like Schizophrenia. I must explain you in simpler way. Schizophrenia is a psychotic illness in which the person has abnormal perception, absurd thinking, decline of higher mental function, deterioration in social and occupational functioning and significant personal sufferings for years. The patient may claim to hear unusual voices which others deny to hear. This is called auditory hallucination. Initially the voices come for a short period and the person feels strange and does not understand what to do. He/ she gradually may start believing on those voices as frequency and intensity of voices increases with passage of time. Often these voices comment/discuss derogatory about the person and sometimes these may suggest or command the person to do certain act. Sometimes the person may harm herself/ himselfs under the infuence of these voices. As you have experienced, she has a self-talking behaviour since last many years, has harmed herself once and now she is claiming a clear two way conversation with that voice. It appears that she is having auditory hallucination(auditory hallucination is one of the commonest symptoms in psychosis like schizophrenia), and apparently these voices are unpleasant or commanding in nature that might have provoked the episode of self harm in past. Since the onset of symptoms are in childhood and has been continuing for years it shows poor awareness of caregiver about the symptoms of illness. It is never too late. You must consult a good child and adolescent psychiatrist and encourage your daughter to discuss her symptoms honestly so that the diagnosis can be finalised. If I would have been her doctor , I would have adviced her for brain imaging, certain other investigations, to take some antipsychotic medicines under supervision of a family member and to attend psycho-educative classes regularly. Medicines and supportive theapy can bring remission to illness. Hope this has helped you. I wish you all the best.