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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Seizure Disorder In An RA Patient And Lack Of Sensation During Urination

Thank you for doing this. My sister aged 47 has been having seizures for the past 5 months. She was being treated for rheumatoid arthritis. In the last 4 years she has been on different meds, latest being mexatreate. Her seizures are frequent sometimes 3 daily. She can feel them coming on and is conscious during them. Some last 5 minutes while others may last 20 minutes. She has had an EEG and MRI. Both have showed nothing. She has recently started to urinate and has no sensation till she feels it on her leg. She has seen a neurologist. I am so concerned. Any thoughts would be very much appreciated. Rhonda
Fri, 28 Jun 2019
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Neurologist,  's  Response
I read your question carefully and I understand your concern.

It is unclear what do you mean by seizure, does she have shaking of the limbs, abnormal sensations etc? At times what you may consider to be a seizure the doctors may consider to be a different phenomenon.
If your doctors agree it is a question of seizures then even if EEG and MRI are normal she should start treatment as epilepsy is first and foremost a clinical diagnosis, it's not made by tests. There are many different treatments for seizures like valproic acid, lamotrigine, levetiracetam, carbamazepine etc, the choice depends on seizure symptoms and should be discussed with the following neurologist.

I hope things will work out for the best.
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Suggest Treatment For Seizure Disorder In An RA Patient And Lack Of Sensation During Urination

I read your question carefully and I understand your concern. It is unclear what do you mean by seizure, does she have shaking of the limbs, abnormal sensations etc? At times what you may consider to be a seizure the doctors may consider to be a different phenomenon. If your doctors agree it is a question of seizures then even if EEG and MRI are normal she should start treatment as epilepsy is first and foremost a clinical diagnosis, it s not made by tests. There are many different treatments for seizures like valproic acid, lamotrigine, levetiracetam, carbamazepine etc, the choice depends on seizure symptoms and should be discussed with the following neurologist. I hope things will work out for the best.