My wife has advanced alz level 5, diagnosed in 2000. She is on half a tab of trimethoprim 300mg at night. She is in a home after 9 years fulltime care at home by me. She had a seizure about 3 months ago. She is nearly blind from the alz. Okay dose? Is it to prevent a seizure? She is 69, diagnosed at 57. See her in doco Stolen Memories (Patricia Hollis). Aricept is working very well over 10 years, with 400mg vitamin E daily.