severe constipation. I have just had a colonoscopy. The doctors found nothing wrong. I then had an endoscopy with many many xray pictures. They found no obstruction. I have gone from one month to three months in the recent past without a bowel movement. After my colonoscopy on October 18,, my doctor tried a new medicine (Amitiza) which I tried for two weeiks 24mg twice a day but no bm. After the endoscopy on Tuesday 6, 2018, he gave me a two week sample of Trulance, 0ne pill once a day. It hasn t moved me yet. What else can we do?