Hi, It may be pompholyx. Pompholyx is a form of hand/foot eczema characterised by vesicles or bullae (blisters). It is a form of vesicular dermatitis of hands and feet, also called vesicular endogenous eczema, and may be the same condition as dyshidrotic eczema. It is sometimes subclassified as cheiropompholyx (hands) and pedopompholyx (feet). You consult the dermatologist for the firm diagnosis. Pompholyx is multifactorial. In many cases it appears to be related to sweating, as flares often occur during hot weather, humid conditions, or following emotional upset. Other contributing factors include-Genetics, Contact with irritants such as water, detergents, solvents and friction, Association with contact allergy to nickel and other allergens,Inflammatory dermatophyte (tinea) infections,Adverse reaction to drugs, most often immunoglobulin therapy...etc I would suggest... - avoidance of suspected triggers - steroids in tappering dose - antihistaminics - application of antibiotic,antifungal or steroid cream as needed - Dettol cleansing I hope this would help you.. Thanks. Dr. Ilyas Patel MD