52 yr old woman, dull pressure left side of chest that comes and goes, ankle swelling, extreme fatigue, sometimes left arm feels tingly, but I also use that arm for computer mouse (not left handed though), regular GP says my insignificant heart murmur is a lot louder. Father and his family have strong history of tortorous aneurysms (subclavian, aortic & abdominal aortic, and problem with Fibrinogen, with aortic dissection... should I be worried? I think they are sending me for echocardiogram. I don t have blue hue in my extremities... I am overweight and work at a desk... but have put on a lot of weight in the last 2 months without changing eating habits.