Thank you for your query. Duodenal ulcers, secondary to H. Pylori infection, need to be monitored closely. The infection should be treated promptly and adequately. The only way of confirming this is by an endoscopy evaluation of the duodenal mucosa to check for the bacteria. Chronic(long term) H. Pylori infection can result in chronic ulcers which may lead to cancer of the duodenum. Concomitant Peptic (gastric) ulcers also need to ruled out. It is vital to have regular follow ups to detect an progression of disease. Proton pump inhibitors are the mainstay of treatment for ulcers. There are some surgical procedures that cut of the signals to stomach that produce acid. This maybe indicated based on the cause of the ulcers. I recommend a review with your gastroenterologist. Make sure to take all your earlier reports. If you have any blood in your stools(black, dark green or red), or have vomiting with blood, go to the ER right away. Hope you feel better and this information helps. Please get back to us for further clarification. Wish you good health